This February psychologists at the University of Cardiff in Wales found that people whose ability to frown is compromised by cosmetic botox injections are happier, on average, than people who can frown. The researchers administered an anxiety and depression questionnaire to 25 females, half of whom had received frown-inhibiting botox injections. The botox recipients reported feeling happier and less anxious in general; more important, they did not report feeling any more attractive, which suggests that the emotional effects were not driven by a psychological boost that could come from the treatment's cosmetic nature.

The concept works the opposite way, too — enhancing emotions rather than suppressing them. People who frown during an unpleasant procedure report feeling more pain than those who do not, according to a study published in May 2008 in the Journal of Pain. Researchers applied heat to the forearms of 29 participants, who were asked to either make unhappy, neutral or relaxed faces during the procedure. Those who exhibited negative expressions reported being in more pain than the other two groups. Lewis, who was not involved in that study, says he plans to study the effect that botox injections have on pain perception. "It's possible that people may feel less pain if they're unable to express it," he says.